Amgen
announces Positive Top-Line Results for Denosumab treatment of Bone Loss in men
with Non-metastatic Prostate Cancer Undergoing Androgen Deprivation Therapy - July 14, 2008
In this study of more than 1,400 men, denosumab treatment produced
statistically significantly greater increases in bone mineral density (BMD) at
the lumbar spine (primary endpoint) and non-vertebral sites compared with
placebo at multiple time points. These improvements in BMD were consistent with
those seen in other denosumab studies evaluating BMD in women with breast
cancer receiving aromatase inhibitor therapy, and in post-menopausal women with
low bone mass.
Bone Loss Prevented by
Risendronate in Breast Cancer Survivors - June 18, 2008
Dr. Susan L. Greenspan of the University of Pittsburgh and colleagues note that
adjuvant
chemotherapy has prolonged disease-free and overall survival in women with
breast cancer. However, chemotherapy-induced early
menopause
is associated with bone loss and osteoporotic fractures.
A Lifelong
Program to Build Strong Bones
There's no cure for osteoporosis, though there are treatments. Like
hypertension, osteoporosis has been called a "silent disease." Thus you may not
be aware of it until you actually fracture a bone. Prevention is the best line
of defense.
Unfortunately, many women think they don't have to start worrying about
osteoporosis until menopause. This a myth. Recent research shows that certain
lifelong habits are the best preventive against osteoporosis. About 45% of a
person's bone mass is formed during the teen years, and indeed young adulthood
or even the teen years are the right time to form the health habits that help
prevent osteoporosis. Still, it's never too late to begin. Bones, like skin,
deserve special care.
Ask the Doctor: Osteoporosis - Health Awareness -
November 25, 2007
Are you one of the eight million women with osteoporosis? If so, you probably
don't spend much time thinking about it. In fact, you may not even know you
have it. This notoriously "silent disease" often goes unnoticed until a simple
bump or fall causes a bone to break or fracture.
Exercise sessions build bone; stave off impact of osteoporosis -
August 16, 2007
A muscular physique reminiscent of Arnold Schwarzenegger had yet to emerge from
Ingeborg Revord.
Not a problem for Revord, a Village of Calumet Grove resident who only recently
sought to begin building bone rather than becoming muscle-bound.
"I know I need to do this," Revord said, gearing up to stretch and exercise,
"because I was surprised to find I had osteoporosis. It is a scary situation."
Lilly's Evista Trims Risk of Certain Breast Cancers<
- July 20, 2007
Eli Lilly & Co.'s osteoporosis drug Evista reduced the risk of certain
invasive breast cancers in post-menopausal women, according to a review by
U.S.
regulators.
Diet, exercise can't stop osteoporosis - July 9,
2007
Strength training, coupled with a diet rich in calcium and vitamin D, does your
body good in many ways - some likely to reduce your risk of bone fracture.
But if you're looking for evidence that diet and exercise can match the
effectiveness of drugs in staving off osteoporosis in middle age, you're going
to be disappointed.